\setupindenting[yes,big,first]

\starttext

\page \input knuth \par \startitemize
    \item \input knuth
\stopitemize \input tufte \par

\page \input knuth \par \startitemize[indenting={yes,first,big}]
    \item \input knuth
\stopitemize \input tufte \par

\page \input knuth \par \startitemize[indenting={yes,first,big},alignsymbol=yes]
    \item \input knuth
\stopitemize \input tufte \par

\page \input knuth \par \startitemize[indenting={yes,next,big}]
    \item \input knuth
\stopitemize \input tufte \par

\stoptext

